Efficacy and safety of gabapentin for uremic pruritus and restless legs syndrome in conservatively managed patients with chronic kidney disease

Journal of Pain and Symptom Management, Apr 2015, vol. 49, no. 4, p. 782-789

Cheikh Hassan, Hicham I, Brennan, Frank, Collett, Gemma, Josland, Elizabeth A, Brown, Mark A

The authors of this study conclude that gabapentin is a viable treatment for conservatively managed CKD and ESKD patients with pruritus and/or RLS, but side effects are common. Gabapentin should be used with caution although higher doses do not appear to be a factor associated with side effects.

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