Tuesday 29 March 2016

The use of corticosteroids in reducing cancer-related fatigue: assessing the evidence for clinical practice

International Journal of Palliative Nursing, Jan 2016, vol. 22, no. 1, p. 5-9
Begley, Sarah, Rose, Kevin, O'Connor, Margaret

A widely used strategy to treat fatigue in palliative care is the use of corticosteroids but, despite being frequently prescribed, evidence of their effectiveness is ambiguous. This paper used a systematic approach to explore literature to determine evidence about whether the use of corticosteroids improves levels of cancer-related fatigue in people with advanced cancer.  The four included studies all reported improvements in patient-reported fatigue as a result of taking corticosteroids, although the quality of results varied and only a few were deemed to have statistically significant results. While there is some evidence that corticosteroids can improve cancer-related fatigue, more rigorous research is required.

Available in print in Arthur Rank Hospice Library, Brookfields Hospital