Tuesday 26 January 2016

Palliative care in patients with ovarian cancer and bowel obstruction

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, Nov 2015, vol. 23, no. 11, p. 3157-3163
Daniele, Alberto, Ferrero, A, Fuso, L, Mineccia, M, Porcellana, V, Vassallo, D, Biglia, N, Menato, G

Malignant bowel obstruction (MBO) is usually a pre-terminal event in patients with ovarian cancer. The authors analyzed medical and surgical procedures, performance status, nutritional status, cachexia, and their prognostic value in this group of patients. Cachexia, low performance status, and poor nutritional status were significant predictors of worse survival after MBO, independent of the treatment. The authors conclude that surgery has to be considered in patients without serious contraindications; otherwise, a medical protocol, including antisecretory drugs, is the standard of care in frail patients.