Tuesday 26 January 2016

Symptom management and end-of-life care in amyotrophic lateral sclerosis

Neurologic clinics, Nov 2015, vol. 33, no. 4, p. 889-908
Jackson, Carlayne E, McVey, April L, Rudnicki, Stacy, Dimachkie, Mazen M, Barohn, Richard J

The number of available symptomatic treatments has markedly enhanced the care of patients with amyotrophic lateral sclerosis (ALS). Once thought to be untreatable, patients with ALS today clearly benefit from multidisciplinary care. Unfortunately, there are few randomized controlled trials of medications or interventions addressing symptom management. In this review, the authors provide the level of evidence, when available, for each intervention that is currently considered standard of care by consensus opinion. 

Fulltext available from Elsevier in Neurologic Clinics