Schmidt-Hansen, Mia; Bennett, Michael I; Arnold, Stephanie; Bromham, Nathan; Hilgart, Jennifer S
The authors of this updated Cochrane review conclude that oxycodone offers similar levels of pain relief and adverse
events to other strong opioids. However, hallucinations occurred less with CR
oxycodone than with CR morphine, but the quality of this evidence was very low,
so this finding should be treated with utmost caution. Our conclusions are
consistent with other reviews and suggest that oxycodone can be used first line
as an alternative to morphine. However, because it is cheaper, morphine
generally remains the first-line opioid of choice.